1. Name Surname

: Doğukan MUTLU

2. Date of Birth

: 10.09.1989

3. Title

: Dr. Öğr. Üyesi

Contact Information

: dogukan.mutlu@uskudar.edu.tr

4. Educational Background

Degree Department University Year
BSc Biyoloji Bölümü Pamukkale Üniversitesi 2012
MSc Biyoloji Anabilim Dalı Pamukkale Üniversitesi 2015
PhD Biyoloji Anabilim Dalı Pamukkale Üniversitesi 2022

5. Academic Titles

Degree Department University Year
Assistant Professor Moleküler Biyoloji ve Genetik Üsküdar Üniversitesi 2024

6. Supervised Theses

7. Publications

7.1. Papers published in internationally refereed journals (Scopus Indexed)

  1. Sahin C., Mutlu D., Erdem A., Kilincarslan R., Arslan S., New cyclometalated iridium(III) complexes bearing substituted 2-(1H-benzimidazol-2-yl)quinoline: Synthesis, characterization, electrochemical and anticancer studies, Bioorganic Chemistry, (2024), 151(107706), 107706, .
  2. ATİKE İ. Y., DOĞUKAN M., SALİH İ. E., ŞEVKİ A., Poorhosein G. s. ., Nesli Y., PINAR K., RECEP L., Polyacrylonitrile (PAN)/carbon nanotube (CNT) electrospun nanofibers: synthesis, characterization, their biocompatibility for L929 fibroblast cells and molecular docking studies, International Journal of Polymeric Materials and Polymeric Biomaterials, (2024), 73(16), 1418-1428, .
  3. AHMET E., DOĞUKAN M., RAFET K., OSMAN D., ŞEVKİ A., Half-Sandwich Ru(II) Complexes Bearing 2-(2'-quinoly)benzimidazoles with Anticancer Activity, Biointerface Research in Applied Chemistry, (2024), 14(4), , .
  4. DOĞUKAN M., CENGİZ İ., ÇİĞDEM Ş., ŞEVKİ A., Cytotoxic and Apoptosis-Inducing Activities of Iridium Complexes Bearing 2-Phenylimidazo[4,5-f][1,10]-Phenanthroline Derivatives in Human Cancer Cells, Pharmaceutical Chemistry Journal, (2024), 58(), 238 - 244, .
  5. Kart N. B., Sulak M., Mutlu D., Kuzucu V., Arslan S., Dogan N. M., Evaluation of Anti-Biofilm and in Vitro Wound Healing Activity of Bacterial Cellulose Loaded with Nanoparticles and Borax, Journal of Polymers and the Environment, (2024), (), , .
  6. SEWGIL S. A., KAREEM A. A., NUR B. K. N., DOĞUKAN M., CEYDA B. R., VOLKAN K., ŞEVKİ A., NAZİME M. D., Evaluation of Antibiofilm and Cytotoxic Activity of Microalgae Isolated from Different Sites of betwata- Erbil/Iraq, Baghdad Science Journal, (2024), 21(11), , .
  7. Meltem G. C., NUR B. K. N., BERNA K. Y., KORAY Ş., DOĞUKAN M., NAZİME M. D., ŞEVKİ A., ABDULKADİR A., Biosourced polymeric cryogels for future biomedical applications with remarkable antimicrobial activities and tribological properties, Materials Today Communications, (2024), 38(), , .
  8. DOĞUKAN M., BATIKAN G., MÜCAHİT S., NUR B. K. N., Gülçin A. M., NAZİME M. D., GÜRKAN S., MELAHAT F. S., ŞEVKİ A., Biological activities of Liquidambar orientalis: Antibiofilm, cytotoxicity, apoptosis, and miRNA expressions, Botanica Serbica, (2024), 48(1), 17 - 26, .
  9. ZEFİNE U., FATİH T., Cansel Ç., Kübra T., GİZEM T. Y., DOĞUKAN M., YUSUF S., Şevki A., Exploring 2-Pyrazoline derivatives as potent antidiabetic agents and cholinesterase inhibitors: Their synthesis and molecular docking studies, Journal of Molecular Structure, (2024), 1315(1), 1 - 10, .
  10. AYSAN L. A., GİZEM T. C., ALPER K., NECATİ Z., ÖZLEM Ö., ŞEVKİ A., DOĞUKAN M., Evaluation of the effect of injectable platelet-rich fibrin (i-PRF) in wound healing and growth factor release in rats: a split-mouth study, Growth Factors, (2024), 42(1), 36 - 48, .
  11. EDA K., YUSUF Ö., DİCLE E. G., DOĞUKAN M., CEM G., ŞEVKİ A., Investigation of controlled drug release of ibuprofen with prepared and characterized innovative bigel materials, Wiley, (2023), 54(12), 1707 - 1716, .
  12. NUR B. K. N., BATIKAN G., DOĞUKAN M., NAZİME M. D., ŞEVKİ A., GÜRKAN S., Evaluating Antibiofilm, Cytotoxic and Apoptotic Activities of Scutellaria brevibracteata subsp. brevibracteata Essential Oil, Chemistry and Biodiversity, (2023), 20(12), e202300878, .
  13. GONCA G., MÜCAHİT S., DOĞUKAN M., Fusaric acid inhibits cell proliferation and downregulates expressions of toll-like receptors pathway genes in Ishikawa endometrial cancer cells, European Review for Medical and Pharmacological Sciences, (2023), 27(), 7431 - 7436, .
  14. KORAY Ş., MUSA Ç., KEMAL Ç., DOĞUKAN M., ŞEVKİ A., PHEMA/PPy cytocompatible conductive cryogels: One-pot synthesis, characterization, and electrical properties, Elsevier BV, (2023), 35(), , .
  15. MÜCAHİT S., DOĞUKAN M., LEVENT E., ŞEVKİ A., Assessing effects of caffeic acid on cytotoxicity, apoptosis, invasion, GST enzyme activity, oxidant, antioxidant status and micro-RNA expressions in HCT116 colorectal cancer cells, Elsevier BV, (2023), 157(), 19 - 26, .
  16. GÜRKAN S., DOĞUKAN M., BATIKAN G., ASLI S., ŞEVKİ A., The anticancer effect of Salvia pisidica essential oil through promotion intrinsic and extrinsic apoptosis pathways in human cancer cell lines, Journal of Herbal Medicine, (2023), 39(), 1 - 6, .
  17. FARID N., AMINA D., NAZİME M. D., ŞEVKİ A., DOĞUKAN M., NARIMANE S., In Vitro Evaluation of Cytotoxic Activity of Algerian propolis against HumanBreast Adenocarcinoma (MDA-MB-231) Cells and Investigation of itsPotential Mechanism of Action, Bentham Science Publishers Ltd., (2023), 19(1), 28 - 38, .
  18. SIDIKA D. K., ÇİĞDEM Ş., DOĞUKAN M., FARID N., ŞEVKİ A., NAZİME M. D., Synthesis, Characterization, Antibiofilm and Anticancer Activity of NewRuthenium Complexes with 2,2-bipyridine-4,4-dicarboxamide, Letters in Organic Chemistry, (2022), 19(11), 1013 - 1022, .
  19. SERKAN K., İBRAHİM D., DOĞUKAN M., NURİ A. M., HAKAN Ü., ŞEVKİ A., New cytotoxic chalcone derivatives from Astragalus ponticus Pall., Natural Product Research, (2022), 36(18), 4666 - 4674, .
  20. EMRAH K., DOĞUKAN M., ÖMRÜYE Ö., ŞEVKİ A., ARİF K., Design, synthesis and pharmacological evaluation of novel Artemisinin-Thymol, Natural Product Research, (2022), 36(14), 3511 - 3519, .
  21. RECEP L., NURİ K. A., MUSTAFA Ö., ŞEVKİ A., DOĞUKAN M., SALİH İ. E., YASER A., Synthesis of water soluble symmetric and asymmetric pillar[5]arene derivatives: Cytotoxicity, apoptosis and molecular docking studies, Journal of Molecular Structure, (2022), 1265(), , .
  22. METİN K., DOĞAN Ç., Didem K. N., CAN Y., CEYLAN F. B., AS A. M., Emrah K., ARİF K., ASLIHAN K. K., ÇİĞDEM O., DOĞUKAN M., Hafis A. A., ŞEVKİ A., Synthesis and biological activity of new indole based derivatives as potent anticancer, antioxidant and antimicrobial agents, Journal of Molecular Structure, (2022), 1263(), , .
  23. ASLIHAN K. K., Neslihan A., ÇİĞDEM O., ARİF K., NEVROZ A. E., ŞEVKİ A., DOĞUKAN M., METİN K., CAN Y., DOĞAN Ç., TUFAN T., NEVZAT Ş., A Novel 4H-Chromen-4-One Derivative from Marine Streptomyces ovatisporus S4702T as Potential Antibacterial and Anti-Cancer Agent, ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, (2022), 22(3), 362 - 370, .
  24. DOĞUKAN M., CANSEL Ç., MEHMET Ö., ŞEVKİ A., Anticancer and apoptotic effects of a polysaccharide extract isolated from Lactarius chrysorrheus Fr. in HepG2 and PANC-1 cell lines, Archives of Biological Sciences, (2022), 74(4), 315-324, .
  25. CAN Y., Othman P. A., CEYLAN F. B., METİN K., DOĞAN Ç., ARİF K., AS A. M., ŞEVKİ A., DOĞUKAN M., ÇİĞDEM O., ASLIHAN K. K., A Thiophene Derivative, 2-Bromo-5-(2-(methylthio)phenyl)thiophene, Has Effective Anticancer Potential with Other Biological Properties, ChemistrySelect, (2022), 7(15), , .
  26. CAN Y., ŞEVKİ A., DOĞUKAN M., METİN K., ABDUSSAMET K., ASLIHAN K. K., ÇİĞDEM O., ÖMRÜYE Ö. A., ARİF K., Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes, Anti-Cancer Agents in Medicinal Chemistry, (2021), 21(10), 1292-1300, .
  27. Aslıhan K., ÇİĞDEM O., CAN Y., ŞEVKİ A., DOĞUKAN M., ARİF K., MUHEB A., ABDUSSAMET K., DOĞAN Ç., METİN K., Synthesis, Cytotoxicity, Antioxidant and Antimicrobial Activity of Indole Based Novel Small Molecules, LETTERS IN DRUG DESIGN & DISCOVERY, (2021), 18(5), 461 - 470, .
  28. ÇİĞDEM Ş., DOĞUKAN M., Farid N., Ghodrat M., I. Z. F., ŞEVKİ A., NAZİME M. D., New iridium bis-terpyridine complexes: synthesis, characterization, antibiofilm and anticancer potentials, BioMetals, (2021), 34(), 701 - 713, .
  29. ŞEVKİ A., KÜBRA K., DOĞUKAN M., GÜRKAN S., Assessment of Cytotoxic and Apoptotic Effects of Salvia syriaca L. in Colorectal Adenocarcinoma Cell Line (Caco-2), IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, (2021), 20(3), 235 - 242, .
  30. METİN K., DOĞAN Ç., CAN Y., ŞEVKİ A., DOĞUKAN M., ASLIHAN K. K., ÇİĞDEM O., ÖMRÜYE Ö., AS A. M., ARİF K., Synthesis, Biological Evaluation and Molecular Docking of Novel Thiophene\u2010Based Indole Derivatives as Potential Antibacterial, GST Inhibitor and Apoptotic Anticancer Agents, ChemistrySelect, (2020), 5(19), 5809 - 5814, .
  31. AMINA D., NARIMANE S., NAZİME M. D., ŞEVKİ A., DOĞUKAN M., İBRAHİM K., SALAH R., SALAH A., Comparative study of antibiofilm, cytotoxic activity and chemical composition of Algerian propolis, Journal of Apicultural Research, (2019), 59(), 160-169, .

7.2. Papers published in other internationally peer-reviewed journals

  1. KAAN H., ŞEVKİ A., NURİ A. M., ADNAN A., İBRAHİM D., DOĞUKAN M., BAHATTİN T., HAKKI A. M., In Vitro Regulation of the Expression of the Sars-Cov-2 Receptor Angiotensin-Converting Enzyme (Ace2) in Lung Cancer Cells by Natural Products, Trakya University Journal of Natural Sciences, (2021), 22(2), 155 - 161, .

7.3. Assertions presented in international scientific congresses and published in the proceedings

  1. CAKIR C., CAM D., ABDELSALAM A. H., TUNA K., MUTLU D., TOKUL-OLMEZ O., AYDOGMUS-OZTURK F., ARSLAN S., OZTURK M., The edible mushroom, Infindibulicybe geotropa (Bull.) Harmaja triggers apoptosis in human colon cancer (Caco-2) cell lines, 12th Aegean Analytical Chemistry Days, (19.10.2023), İstanbul-Türkiye
  2. SARKAYA K., MUTLU D., Phytic acid immobilized cryogels: Studying the effect on the L929 cell proliferation for biomedical applications, 6th International Eurasian Conference on Biological and Chemical Sciences, (11.10.2023), Ankara-Türkiye
  3. MUTLU D., ABDELSALAM A. H., KOZANSOY C., ARSLAN Ş., Effects of thymol on colony formation and apoptosis induction of human ovarian cancer cells, 3rd International Mediterranean Scientific Research and Innovation Congress, (26.08.2023), Antalya-Türkiye
  4. MUTLU D., Cytotoxicity and cell cycle analysis of usnic acid on human endometrial carcinoma cells, 3rd International Congress on Contemporary Scientific Research, (07.08.2023), Adana-Türkiye
  5. MUTLU D., An investigation on the in vitro wound healing activity and cytotoxicity of o-coumaric acid on human hepatoma cells, 7th International Conference on Medical & Health Sciences, (06.08.2023), Ordu-Türkiye
  6. CAKIR C., CAM D., AYDOGMUS-OZTURK F., SICAK Y., MUTLU D., ARSLAN S., OZTURK M., Tricholoma scalpturatum’un meme kanseri (MCF-7) hücre hattına karşı sitotoksik aktivitesi., 5th International Eurasian Conference on Biological and Chemical Sciences, (23.11.2022), Ankara-Türkiye
  7. GÜNAL B., MUTLU D., ARSLAN Ş., ( G. S., Anti-inflammatory Effects of Essential Oil Extracted from Salvia syriaca L. on RAW264.7 Cells, 3rd International Congress on Plant Biology., (21.09.2022), Rize-Türkiye
  8. SEGUENI N., DAIKH A., NASIRLI F., DOGAN N. M., ARSLAN S., MUTLU D., In vitro inhibition of human breast cancer adenocarcinoma cell by propolis via induction of intrinsic pathway of apoptosis, The Seventh International Mediterranean Symposium on Medicinal and Aromatic Plants, (18.11.2021), İzmir-Türkiye
  9. KABALAY B., MUTLU D., ARSLAN Ş., SEMİZ G., KOCABIYIK K., Essential Oil Composition Analysis and Cytotoxic Activity of Salvia frigida Boiss. from Turkey, The 4rd International Symposium on EuroAsian Biodiversity, (03.07.2018), Ukrayna-Kiev
  10. MUTLU D., ARSLAN Ş., KABALAY B., TERZİOĞLU G., TÜFEKÇİ A. R., DEMİRTAŞ İ., Chemical Constituent of Small Nettle (Urtica urens) Seed Oil and Its Cytotoxic Activity, The 4rd International Symposium on EuroAsian Biodiversity, (03.07.2018), Kiev-Ukrayna
  11. KABALAY B., MUTLU D., ARSLAN Ş., SEMİZ G., KOCABIYIK K., Chemical composition and Cytotoxicity of Nepeta nuda subsp. lydiae P. H. Davis Essential Oil Towards Colon Carcinoma, The 4rd International Symposium on EuroAsian Biodiversity, (03.07.2018), Kiev-Ukrayna
  12. MUTLU D., ARSLAN Ş., AKŞİT H., DEMİRTAŞ İ., Luteolin Dependent Inhibition of CYP1A1: Application of in vitro and in Silico Modeling Approaches, The 4rd International Symposium on EuroAsian Biodiversity, (03.07.2018), Kiev-Ukrayna
  13. MUTLU D., AKŞİT H., DEMİRTAŞ İ., ARSLAN Ş., In vitro assessment of human CYP1A1 inhibition potential of Resveratrol and Silychristin, 9th Congress of the Turkish Toxicology Society, (21.10.2015), İzmir-Türkiye
  14. KASKA Y., SEZGIN Ç., SECME M., SARI F., BAŞKALE E., SÖZBILEN D., ULUBELI S. A., DÜŞEN S., MUTLU D., ERYIĞIT A., ERGUN G., Increasing nesting activity of loggerhead turtles (caretta caretta) on Dalyan Beach, Turkey during 2008-2014 nesting seasons: an encouraging trend, 35th Annual Symposium on Sea Turtle Biology and Conservation, (22.04.2015), Muğla-Türkiye

7.4. International books or chapters

7.5. Papers published in national peer-reviewed journals

  1. DOĞUKAN M., NEVİN K. D., NUR B. K. N., ŞEVKİ A., Phenolic Acids Modulating Epigenetic Mechanisms in HepG2 Human Hepatoma Cells, Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, (2024), 14(2), 604-615, .
  2. NAZLI Ç., GÜLÇİN M., DOĞUKAN M., CİHAN K., ÜMİT Ç., VEYSEL F. İ., Expression of sialic acid binding receptors (siglecs) in human trophoblast cell line, Pamukkale Tıp Dergisi, (2024), 17(2), 195-203, .
  3. İBRAHİM D., TEVFİK Ö., Sarmed M., DOĞUKAN M., ŞEVKİ A., Functional Food Components and Activities of Pinus nigra and Pinus sylvestris Barks as Food Supplements, International Journal of Chemistry and Technology, (2023), 7(2), 229 - 238, .
  4. DOĞUKAN M., MÜCAHİT S., ŞEVKİ A., Anticancer Effects of Alpha-lipoic Acid on A172 and U373 Human Glioblastoma Cells, Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, (2023), 13(2), 851 - 857, .
  5. DOĞUKAN M., MÜCAHİT S., ŞEVKİ A., Effects of Usnic Acid on Cytotoxicity, Colony Formation and Migration in SK-UT-1 Human Uterine Leiomyosarcoma Cells, Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi, (2023), 18(3), , .

7.6. Assertions presented in national scientific congresses and published in the proceedings

  1. KAVAK E., ARICI Ö. Ö., MUTLU D., ARSLAN Ş., KIVRAK A., Artemisinin-Timol Hibrit Molekülünün Sentezi, Sitotoksititesinin Belirlenmesi ve In Silico Çalışmaları, 32. Ulusal Kimya Kongresi, (17.09.2020), ESKİŞEHİR

7.7. Other publications

Books published by national publishers

Book chapters published by national publishers

  1. ARSLAN S., MUTLU D., Kanser tedavisi için arı zehri ve melittin’in terapötik potansiyeli, (2021), ISBN: 978-625-401-497-0.

8. Projects

9. Administrative Duties

  1. Bölüm Başkan Yardımcısı / Deputy Head of Department - Moleküler Biyoloji ve Genetik (Türkçe) Bölüm Başkan Yardımcısı (2024-Continues)
  2. Öğrenci Danışmanlığı / Student Adviser - 51-60 Öğrenci Danışmanlığı (2024-Continues)
  3. Komisyon Üyesi / Member of Commission - Staj Komisyonu (Enstitü / Fakülte / MYO) (2024-Continues)
  4. Komisyon Üyesi / Member of Commission - Erasmus ve Dış İlişkiler Komisyonu (2024-Continues)

10. Scientific Memberships

11. Awards

12. Coourses recently given

Academic Year Semester Course name Hours Number of Students
Theoretical Application
2023-2024 Spring  
Fall  

Created: 21.11.2024